Figure 1, The steps of regenerative medicine. - StemBook - NCBI

The production of cellular therapies requires the optimization of four steps: first, isolating and culturing cells that can be readily obtained from a patient in a non-invasive fashion. Second, the reprogramming of these cells into a pluripotent state. Third, the directed differentiation of those patient-specific pluripotent cells into the cell type relevant to their disease. And, fourth, techniques for repairing any intrinsic disease-causing genetic defects and transplantation of the repaired, differentiated cells into the patient. Notably, these disease-relevant patient cells can also be used for in vitro disease modeling which may yield new insights into disease mechanisms and drug discovery.

Frontiers Regenerative Medicine Therapy in Malaysia: An Update

Immunological considerations for cell therapy using human

Identification of hurdles in the development of cell-based

Figure 2, Cell-autonomous mechanisms. - StemBook - NCBI Bookshelf

Cell differentiation - Definition and Examples - Biology Online

Figure 8, An example of hepatoblast delamination. - StemBook

PDF) Regenerative Medicine and Tissue Engineering: Advancements

Pharmaceutics, Free Full-Text

Frontiers Regenerative medicine technologies applied to

Lancet Commission: Stem cells and regenerative medicine - The Lancet

Differential role of natural killer group 2D in recognition and