Drug-Like Molecules Regenerate Hair Cell-Like Cells in Adult Mice — Hearing Health Foundation

“Think about a brake when driving a car,” Chen explains. “If the brake is always engaged, you can’t drive. We found an siRNA that could remove the brake in this genetic pathway.”

Hearing Health Foundation (HHF) is the largest non-profit funder of hearing research. Since 1958, HHF has given away millions of dollars to hearing and balance research, including work that led to cochlear implant technology and now through the Hearing Restoration Project is working on a cure for hearing loss and tinnitus. HHF also publishes Hearing Health magazine, a free consumer resource on hearing loss and related technology, research, and products.

Reprogramming inner ear to regrow hair cells promising target for

Selective ablation of cochlear hair cells promotes engraftment of

Generation of inner ear hair cells by direct lineage conversion of

Lgr5+ cells regenerate hair cells via proliferation and direct

Colonies of Inner Ear Progenitor Cells Generate Hair Cells In

Frontiers G protein-coupled receptors in cochlea: Potential

Identification of mouse cochlear progenitors that develop hair and

Pharmaceuticals, Free Full-Text

Specific Group of Cochlear Cells in Mice Demonstrate Regenerative

Generation of inner ear hair cells by direct lineage conversion of

Normal Development and Formation of Hair Cells in Both Wild-Type

Highlights From the Hearing Restoration Project — Hearing Health