CleanPlex Limb-Girdle Muscular Dystrophy NGS Panel • NUCLEUS BIOTECH

NUCLEUS BIOTECH • CleanPlex Limb-Girdle Muscular Dystrophy NGS Panel
The CleanPlex® Limb-Girdle Muscular Dystrophy NGS Panel for Illumina® or Ion Torrent™ is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 38 genes associated with Limb-Girdle Muscular Dystrophy. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads. This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries. You have the option to modify the existing content of this pre-designed panel. Please contact us for a quote.

Limb-girdle muscular dystrophies — international collaborations for translational research

Duchenne Muscular Dystrophy, DMD - The Medical Biochemistry Page

The Latin American experience with a next generation sequencing genetic panel for recessive limb-girdle muscular weakness and Pompe disease, Orphanet Journal of Rare Diseases

Limb-girdle muscular dystrophies — international collaborations for translational research

Impact of next‐generation sequencing panels in the evaluation of limb‐girdle muscular dystrophies - Özyilmaz - 2019 - Annals of Human Genetics - Wiley Online Library

Dystrophinopathies and the Limb-Girdle Muscular Dystrophies - Practical Neurology

The CleanPlex® Limb-Girdle Muscular Dystrophy NGS Panel for Illumina® or Ion Torrent™ is a pre-designed and made-to-order multiplex PCR /

CleanPlex Limb-Girdle Muscular Dystrophy NGS Panel

Novel compound heterozygous mutations in the TTN gene: elongation and truncation variants causing limb-girdle muscular dystrophy type 2J in a Han Chinese family

Clinical, pathological, imaging, and genetic characterization in a Taiwanese cohort with limb-girdle muscular dystrophy, Orphanet Journal of Rare Diseases

Efficient engraftment of pluripotent stem cell-derived myogenic progenitors in a novel immunodeficient mouse model of limb girdle muscular dystrophy 2I, Skeletal Muscle

Molecular mechanisms of muscular dystrophies: old and new players

Limb Girdle Muscular Dystrophy Variant Curation Expert Panel - ClinGen

CleanPlex® Limb-Girdle Muscular Dystrophy Panel

Limb-girdle Muscular Dystrophies - ScienceDirect

Interventions for muscular dystrophy: molecular medicines entering the clinic - The Lancet