By A Mystery Man Writer
Obese adolescents have an increased risk of developing multiple sclerosis (MS), and this result suggests that prevention of adolescent obesity may contribute to reduced MS risk. Objective: To examine whether obesity during childhood, adolescence, or adulthood is associated with an increased risk of multiple sclerosis (MS). Methods: Women in the Nurses’ Health Study (n = 121,700) and Nurses’ Health Study II (n = 116,671) provided information on weight at age 18 and weight and height at baseline, from which body mass index was derived. Women also selected silhouettes representing their body size at ages 5, 10, and 20. Over the total 40 years of follow-up in both cohorts combined, we confirmed 593 cases of MS. Cox proportional hazards models, adjusting for age, latitude of residence, ethnicity, and cigarette smoking, were used to estimate the rate ratios and 95% confidence intervals (CI). Results: Obesity at age 18 (body mass index ≥30 kg/m2) was associated with a greater than twofold increased risk of MS (multivariate relative riskpooled = 2.25, 95% CI: 1.50-3.37, p trend <0.001). After adjusting for body size at age 20, having a large body size at ages 5 or 10 was not associated with risk of MS, whereas a large body size at age 20 was associated with a 96% increased risk of MS (95% CI: 1.33-2.89, p trend = 0.009). No significant association was found between adult body mass and MS risk. Conclusions: Obese adolescents have an increased risk of developing multiple sclerosis (MS). Although the mechanisms of this association remain uncertain, this result suggests that prevention of adolescent obesity may contribute to reduced MS risk. 25(OH)D = 25-hydroxyvitamin D; BMI = body mass index; CI = confidence interval; MS = multiple sclerosis; NHS = Nurses’ Health Study; NHSII = Nurses’ Health Study II; RR = relative risk.
Eating Disorders in Teens
Eating Disorders in Teens
Eating Disorder Statistics - National Eating Disorders Association
Full article: Body mass index in patients with Multiple Sclerosis: a meta-analysis
Dense Breasts: Answers to Commonly Asked Questions - NCI
Bungee Workout: Benefits, Risks, What To Expect
Body mass index trajectories in pediatric multiple sclerosis - Brenton - 2019 - Developmental Medicine & Child Neurology - Wiley Online Library
Body mass index - Wikipedia
Adjusting for BMI in analyses of volumetric mammographic density
39 Types of Diversity in the Workplace to Know
JFMK, Free Full-Text
Your Patients with Multiple Sclerosis have Set Wellness as a High Priority— And the National Multiple Sclerosis Society is Responding - touchNEUROLOGY